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Autosomal Dominant Polycystic Kidney Disease
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Jared J. Grantham, M.D.

Shortly after being elbowed in the flank during a pickup basketball game, a 35-year-old healthy man has severe, colicky abdominal pain followed by gross hematuria. He is hospitalized, and a renal ultrasound scan reveals bilateral polycystic kidneys and liver cysts, previously unknown to the patient. The blood pressure is 160/100 mm Hg. The serum creatinine concentration is 0.9 mg per deciliter (80 . . .

N Engl J Med 359:1477, October 2, 2008 Clinical Practice